What Does Skin Out Mean

What Does Skin Out Mean – Studies have shown that HS is associated with an increased risk of squamous cell carcinoma. It’s a small opportunity, but there are many ways to save it.

Hidradenitis suppurativa can be linked to skin cancer – even where the sun doesn’t shine. Adobe Stock

What Does Skin Out Mean

People with hidradenitis suppurativa (HS), an inflammatory skin condition that causes painful skin rashes and deep ulcers, are aware of other health problems. Some examples are permanent scars, as well as depression and anxiety caused by a perceived chronic condition.

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There is one form of HS that is less well known: squamous cell carcinoma (SCC). It’s a little scary, but worth a look. If you live in HS, the best way to prevent problems is to learn all you can about it and use that information to improve your management of the situation. You should know the connection between HS and skin cancer.

Squamous cell carcinoma is not a cancer that originates from the skin cells in the upper or middle layer of the skin. After basal cell carcinoma, SCC is the second most common type of skin cancer, according to the Skin Cancer Foundation. It is usually caused by excessive exposure to UV rays.

Squamous cell carcinoma is curable if detected and treated early. About 2,000 people die each year in the United States from basal and squamous cell carcinoma, according to the American Cancer Society.

Fara Succaria, assistant professor of dermatology at Johns Hopkins University School of Medicine in Baltimore said, “If left untreated, squamous cell carcinoma can become locally aggressive and aggressive, kill the skin and nearby tissues.” In other words, it can metastasize (spread) causing serious damage and even death.

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Also, SCC is usually too much sunlight. This can happen in people with HS where the SCC develops in areas of the skin that are not hidden by a piece of skin or clothing. Other factors affect how squamous cell carcinoma grows and behaves when associated with HS.

Their main focus is inflammation, which can lead to any type of cancer, said Luis Andres Garza, MD, professor of dermatology at Johns Hopkins University School of Medicine in Baltimore. Inflammation in the body caused by HS may be part of the risk factor for squamous cell carcinoma, he added.

Certain HS medications increase the risk of SCC. Some HS drugs suppress the immune system, for example, which has been linked to a higher risk of skin cancer, Dr. Garza said. For example, one study found that immunosuppression is an independent risk factor associated with worse outcomes in people with squamous cell carcinoma.

Another unique feature of HS squamous cell carcinoma is its location. Rita Pichardo, MD, a dermatologist at Atrium Health Wake Forest Baptist in Winston-Salem, North Carolina, who operates the HS Clinic, says: “The focus is on the skin area. rubbing.” “These areas can be chronically inflamed for years, which makes certain parts of the body — the stomach, abdomen, and pelvis — vulnerable to skin cancer.

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In fact, a research study published in the International Journal of Dermatology in 2021 examined SCC due to HS, and the most common cancers are buttocks, stomach, and genital.

SCC can spread and be even more fatal in people with HS than in healthy people. For example, in a 2021 study, more than half of people (especially men) with HS, who develop squamous cell growth, develop metastatic cancer. More than 40% of them develop recurrence of SCC, and more than 58% die due to metastasis and sepsis.

Finally, Garza added, the chronic scarring, or permanent damage that characterizes HS, is associated with squamous cell carcinoma, a type of skin cancer. Called Marjolin’s lesion, this is a rare and aggressive skin cancer that begins in the skin, with chronic scarring, and inflammation.

Squamous cell carcinoma may be a unique problem in HS because lesions from both conditions are often similar, and skin cancer may be overlooked, according to a case study published in 2020 in the journal Advances in Skin and Wound Care.

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Dr. Pichardo says it’s especially important for people with HF to see a dermatologist every six to 12 months for a comprehensive cancer screening. Still, “It’s hard for a doctor to diagnose skin cancer just by looking at it,” Garza said, “so we’ll do a biopsy and everything that’s important.”

It’s also a good idea to do a self-examination between physical exams. Garza advises that once a month you should check your skin, look in the mirror for places you can’t see, and look for anything different or new. “Trust your instincts,” he added. “If something is different or something you haven’t seen before, see your doctor.”

Some signs to look for: “A spot that bleeds itself on the skin is a red flag,” Garza says. It’s not common for people with HS to see a large scar coming out of the skin, but if there’s more blood around the skin, it should be checked.

Also, see your doctor if there are lumps that do not go away and / or look special in the area of ​​HS lesions that are getting worse with treatment, Garza says.

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There are simple ways to reduce the risk of skin cancer associated with HS.

Get checked out as soon as possible. If you experience symptoms of HS, such as painful cyst-like nodules or lumps on your hips, thighs, or buttocks, see a dermatologist right away. The sooner the treatment began, the less inflammation.

Follow your management plan to a T. “There’s no research to show that good HS management reduces the risk of skin cancer, but it can happen,” Garza said.

Prevents tanning. This means staying out of direct sunlight as much as possible, wearing sunglasses and a hat with a visor, and applying sunscreen to exposed skin, even on cloudy days.

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Most importantly, Garza says, “If you have HS, it’s good to be aware of your skin cancer risk, so it’s important to see your dermatologist regularly and take care of your health. This includes controlling the disease, maintaining a healthy diet, and maintaining a healthy lifestyle.” general health.

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