What's The Worst Disease You Can Get

What's The Worst Disease You Can Get – Children affected by the 1973 smallpox outbreak in Bangladesh were characterized by blistering blisters and abdominal pits or pits.

The last naturally occurring case was identified in October 1977, and the World Health Organization (WHO) recognized the disease globally in 1980.

What's The Worst Disease You Can Get

What's The Worst Disease You Can Get

Over several days, the skin rash turns into blisters characteristic of TDS on the abdomen.

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In 18th-century Europe, it was estimated that 400,000 people died each year from the disease, and a third of the blind were infected with smallpox.

The term “smallpox” was first used in England in the early 16th century to distinguish between syphilis and a disease. It is called “bigness”.

Patient mortality (CFR) and smallpox frequency by type and immunization status based on case studies.

There are two forms of smallpox virus, the most serious and common form is Variola major. It is accompanied by a very penetrating rash and high fever. A less serious disease is usually individual smallpox. Historical mortality of less than 1%.

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Also, a form called variola sinus asphaltione (smallpox without rash) is more common among vaccinated people. This form represents a fever that develops after a normal incubation period. This can only be confirmed by antibody studies. Or it is very rare in culture.

Also, two types of smallpox are extremely rare and serious: cancerous (equilibrium) and hemorrhoidal. Often death

Initial symptoms are similar to those of other persistent viral illnesses such as influenza and the common cold. Fever of at least 38.3°C (101°F), myalgia, malaise, headache, and fatigue (often involving the gastrointestinal tract). Nausea, vomiting and back pain are common. The first bulb stage usually lasts 2-4 days. The first visible lesions in 12-15 days – small red spots. The so-called Anthem – appears on the mucous membranes of the mouth, tongue, palate and throat, and the temperature drops to normal. These lesions can rapidly enlarge and rupture. By releasing large numbers of viruses into the saliva

What's The Worst Disease You Can Get

The smallpox virus attacks skin cells and causes acne or blemishes. A disease-related rash appears 24 to 48 hours after mucosal lesions develop. Usually, spots first appear on the forehead. It spreads quickly on the face. From the ends of the nodes, to the trunk and finally to the distal nodes, this process takes no more than 24 to 36 hours, after which no new lesions appear.

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At this stage, a large variola infection can have a very different course. As a result, there are four types of smallpox according to Rao’s classification.

Simple, variant, malignant (or restricted) and hemorrhagic smallpox In the past, the overall mortality rate for common smallpox was about 30%, and the insidious hemorrhagic form was often fatal. The modified form is rarely fatal. In early bleeding, bleeding occurs before skin lesions develop.

In this form of the disease, blood cells are congested by the second day of the rash. On the third or fourth day, the congestion became filled with a cloudy fluid that turned into a cyst. The fluid becomes cloudy and blisters within 24-48 hours.

On the sixth or seventh day, all skin lesions become blisters, and between the sev and d days the blisters mature and reach their maximum size. The blisters popped up quickly. They are usually round, hard and firm to the touch. Blisters are embedded deep in the skin. It makes the skin feel like little grains, and the fluid drains slowly from the blisters. By the second week, the blisters will begin to loosen and dry. Scabs or scab formation In 16-20 days, scabs form over the entire lesion. It leaves a faint scar and begins to peel

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Typical smallpox is an intermittent rash with prominent blisters on discrete skin surfaces. Rash distribution is more facial dse, forearm than trunk, and distal than proximal dser. Mostly palms and feet are affected, sometimes blisters are formed. A confluent rash occurs that begins to separate the epidermis from the subcutaneous tissue. In a series of cases, the mortality rate from association with smallpox was 62%.

State the nature of the difference and the rate of growth. Varicella smallpox mainly occurs in previously vaccinated individuals. It is very rare in unvaccinated people. A case study shows 1-2% of corrected cases. About 25% were vaccinated. In this form, the disease continues, but may be less severe than the common disease. There is usually no fever during the rash. Skin lesions develop less frequently and grow faster. It is only superficial. It may not reveal the typical features of smallpox.

Atypical smallpox is rarely fatal. This form of variola major is most easily confused with chicken pox.

What's The Worst Disease You Can Get

In 1896 Baker died of necrotizing smallpox in an outbreak in Gloucester, eight days after admission to hospital.

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In malignant smallpox, the lesion is almost red on the skin, whereas in normal types, cysts form. It is not known why some people develop this type, but in the past, it accounted for 5-10% of cases, most (72%) in children.

Malignant smallpox is characterized by high fever followed by an acute prodromal stage lasting 3-4 days. and severe symptoms of viremia. Prodromal symptoms persist after the onset of the rash.

A rash (in the countries) spreads over the mucous membranes and the skin lesions develop slowly. Accumulation or depletion usually occurs. By the eighth or eighth day the lesion is flat and appears embedded in the skin. There is very little fluid in the gallbladder. Unlike common smallpox, which is tender to the touch and may bleed, acute smallpox is often fatal and usually results in death within 8 to 12 days and often 1 to 2 days before death. The lesion becomes grayish-gray in color. A poor prognosis with abdominal distribution.

This pattern is thought to result from cell-mediated immune deficiency against smallpox. As the person heals, the sore will gradually disappear and no scarring or scabbing will occur.

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Hemorrhagic smallpox is a bleeding form of the skin, mucous membranes, gastrointestinal tract, and intestines. This form occurs in two parts of the infection and mainly occurs in adults.

Hemorrhagic smallpox usually does not blister. Bleeding under the skin will burn and appear dark.

The vaccine does not provide immunity against both types of hemorrhagic smallpox. And there are some cases among people who were vaccinated long ago. It has two forms

What's The Worst Disease You Can Get

Badit is described as a Christian Scientist who was not vaccinated against hemorrhagic smallpox, often between 1957 and 1957. “Before I got big, I thought I could do it with the power of my mind.”

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Primary or progressive hemorrhagic smallpox (called purpura) begins at an advanced stage characterized by high fever. Severe headache and abdominal pain

The skin becomes black and red. Petechiae and hemorrhages occur rapidly in the skin, conjunctiva, and mucous membranes. Death often occurs within 5 to 7 days of onset. Some people with small skin lesions live longer than a few days. During that time, the skin peels off and fluid accumulates under the skin. Explosive individuals with minor injuries remain conscious before or shortly before death.

Autopsy revealed petechiae and hemorrhages in the spleen, kidney, serous membrane, skeletal muscle, pericardium, liver, reproductive organs, and bladder.

This pattern is more likely to occur in pregnant women than in the general population.

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Then there is hemorrhagic smallpox. Prodromal symptoms are severe and resemble those seen in early hemorrhagic smallpox. Fever during illness.

Bleeding appears during the first eruption. The rash is usually flat and does not progress beyond the blister stage. Mucus bleeding is less common than the previous type of bleeding.

Sometimes the rash forms blisters that bleed at the base, and the same process develops as common smallpox. This form of the disease is characterized by a decrease in all components of the coagulation cascade and an increase in circulating antithrombin.

What's The Worst Disease You Can Get

This form of smallpox occurs in 3-25% of cases.

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